“More and more Mississippians are using a horse de-wormer medication as an at-home treatment for COVID-19, and it’s causing a spike in calls to poison control.”

Mind you, this poisoning is sending more people toward the hospitals that are already at capacity in that state!

Yeah, they’re afraid of the vaccine, but they’re totally OK with filling their bodies with horse de-wormer, so they just pop down to the feed store and pick some up. Talk about thinning the herd!

I also read somewhere that Trump is now saying he was right about hydroxychloroquine, even though there are now controlled clinical trials showing that the drug not only failed to improve patient care, but actually made matters slightly worse! (One cannot fairly say that it hurt because the slightly worse rates of death, intubation and hospitalization were not statistically significant. A fair conclusion is that it did not help.)

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Notes:

1. This horse dewormer business started before the vaccines were available. See this report from Nevada. “Feed stores are having trouble keeping the medication in stock.”

2. There is some vague logic to the use of this dewormer (ivermectin). Ivermectin has been tested to inhibit the spread of the virus in vitro, but at a dosage many times that prescribed for humans for parasitic infections. Some studies show that ivermectin may also be effective in vivo, and there is a chance that it may someday be approved for treating viral diseases, although the evidence is still insufficient. Researchers have predicted a low likelihood of success against COVID at the current prescribed level for humans, but some evidence at least suggests that higher doses might have some value. But the effective dose may be so large that it might produce dangerous side effects.

The NIH says:

“Pharmacokinetic and pharmacodynamic studies suggest that achieving the plasma concentrations necessary for the antiviral efficacy detected in vitro would require administration of doses up to 100-fold higher than those approved for use in humans”

Trials are still needed to test both the safety and efficacy of various doses. It should go without saying that you should not be stocking up on it from your feed store and taking a horse-strength dosage on your own authority.